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Our experts have assembled a catalog of 485 research publications verifying the health claims of our ingredients

  • We ensure every ingredient is backed by trusted research

    Most dog supplements rely on generic ingredients and anecdotal claims. We’re taking the opposite approach, to guarantee that all of our ingredients are backed by verifiable research publications.

Study

Effectiveness of L-theanine and behavioral therapy in the treatment of noise phobias in dogs.
Michelazzi, M. et al (2010). Journal of Veterinary Behavior, 5(1), 34–35
Participants
20 dogs with noise phobias
Length
63 days
Institute
Università degli Studi di Milano
Type
Randomized

Study

Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon
Withee, E. D. et al (2017). J Int Soc Sports Nutr, 14(1)
Participants
22 healthy adults
Length
23 days
Institute
Helfgott Research Institute, National University of Natural Medicine
Type
Placebo-controlled, Double-blind, Randomized

Study

Improvement of periodontal status by green tea catechin using a local delivery system: A clinical pilot study.
Hirasawa, M. et al (2002). J Periodontal Res, 37(6), pp. 433–438.
Participants
6 humans, 41 - 64 years old diagnosed with advanced periodontitis
Length
8 weeks
Institute
Nihon University School of Dentistry at Matsudo
Type
Placebo-controlled, Randomized

Study

Harmonease Chewable Tablets reduces noise-induced fear and anxiety in a laboratory canine thunderstorm simulation
DePorter, T. et al (2012). Journal of Veterinary Behavior, 7(4), pp.225-232.
Participants
20 healthy adult Beagle dogs
Length
21 days
Institute
University of Toronto
Type
Placebo-controlled, Double-blind,