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  • MSM

    Soothes skin and supports joints

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What is it?

MSM is a natural sulfur often found in vegetables and fruit.

What does it do?

MSM helps to reduce pain and inflammation, prevent allergic reactions, maintain healthy immune cells and support hair growth.

Why we chose it

Along with providing multiple health benefits, MSM has been widely studied in humans with substantial numbers of research publications behind it.

Why not a generic MSM?

Unparalleled in purity, our MSM is both the cleanest and the only one to be approved by the FDA.


Key Findings

Healthy adults running a half marathon showed lower joint pain post-race when taking OptiMSM®, compared to placebo.

Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon
Withee, E. al (2017). J Int Soc Sports Nutr, 14(1)
22 healthy adults
23 days
Helfgott Research Institute, National University of Natural Medicine
Placebo-controlled, Double-blind, Randomized

Further Research

Sulfur in Human Health
Hewlings, S. et al (2019). EC Nutrition, 14.9, 785-791.
Effects of methylsulfonylmethane supplementation on oxidative stress, muscle soreness, and performance variables following eccentric exercise
Melcher, D. et al (2017). Gazzetta Medica Italiana Archivio per le Scienze Mediche, 176(5), pp. 271-83.
Methylsulfonylmethane is effective against gastric mucosal injury
Amirshahrokhi, K. et al (2017). European Journal of Pharmacology, 811, 240–248.
MSM enhances LPS-induced inflammatory response after exercise
Godwin, S. et al (2015). J Int Soc Sports Nutr, 12(S1).
Effects of Oral Supplementation With Methylsulfonylmethane on Skin Health and Wrinkle Reduction
Anthonavage, M. et al (2015). Natural Medicine Journal., Vol 7 (11).
The Effect of Methylsulfonylmethane on Osteoarthritic Large Joints and Mobility
Pagonis, T. et al (2014). International Journal of Orthopaedics, 1. 1-6.
Effect of Single Dose Administration of Methylsulfonylmethane on Oxidative Stress Following Acute Exhaustive Exercise.
Nakhostin-Roohi, B. et al (2013). Iranian Journal of Pharmaceutical Research, 63(10), pp. 1290–1294.
Effect of Methylsulfonylmethane Pretreatment on Aceta-minophen Induced Hepatotoxicity in Rats
Bohlooli, S. et al (2013). Iranian journal of basic medical sciences, 16(8), 896–900.
Effect of Methylsulfonylmethane on Paraquat-Induced Acute Lung and Liver Injury in Mice
Amirshahrokhi, K. et al (2013). Inflammation, 36(5), 1111–1121.